A study from the Northern Manhattan Study has found new evidence regarding the relationship of low vitamin D levels with the incidence of atherosclerosis. Their results show that levels of 25-hydroxyvitamin D levels will increase hardening of the intima-media thickness and carotid plaque as a result. It is delivered by a senior researcher Dr. Shonni Silverberg, from the Columbia University College of Physicians and Surgeons, New York, published in the journal Stroke in August 2011.
They also found that 25-hydroxyvitamin D was inversely with intima media thickness (beta, -0.01 per increase 10-ng/mL; P = 0.05) and carotid plaque thickness (beta, -0.10 increase per 10 - ng / mL, P = 0.03). In the model containing risk factors for heart disease and an index of mineral metabolism, 25-hydroxyvitamin D
accounted for 13% of the thickness of the intima-media thickness and carotid plaque.
Researchers enrolled 203 adults who measured vitamin D serum levels and carotid ultrasonography. They measured levels of 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D, calcium, phosphorus, and parathyroid hormone. After adjusting for cardiovascular risk factors, the researchers found that the amount of plaque was associated with higher levels of phosphorus (beta, 0.39 per increase 1-mg/dL; P = 0.02) and calcium-phosphorus (beta, 0.36 per increase of 10 -U, P = 0.03). The majority (57%) of them had experienced plaque, and the researchers found an association between the number of plaques with high levels of phosphorus and calcium-phosphorus.
Adopted from www.usagainstathero.com
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