Showing posts with label Diabetes.. Show all posts
Showing posts with label Diabetes.. Show all posts

Saturday, July 2, 2011

Effect of Beta-blockers in Patients with Chronic Heart Failure and COPD

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A study conducted by dr. Christopher Hayward and colleagues from St. Vincent's Hospital, Sydney, Australia, showed that patients with an unstable hemodynamic condition has a better tolerance with carvedilol therapy and patients with a history of respiratory disease (which need inhalation therapy) are more able to tolerate treatment with bisoprolol and metoprolol. This conclusion is the result of research conducted by Dr. Christopher Hayward and colleagues from St. Vincent's Hospital, Sydney, Australia. The results of this study have also been published in the Journal of the American College of Cardiology 2010, edition 27.
Carvedilol, which is included in the class of nonselective beta-blocker bisoprolol and / metoprolol, which include beta blockers selective and has long been used as a therapy for patients with chronic heart failure.

Wednesday, June 29, 2011

Effect watching television on the health

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Watching television (TV) is prolonged and frequent behavior and pervasive in individuals in industrialized countries and has been associated with increased morbidity and mortality. This was the conclusion of a meta-analysis conducted Grøntved A,. et al., published in the Journal of the American Medical Association in 2011. In the study mentioned watching television in a long time will increase the risk of type 2 diabetes mellitus, cardiovascular disease and risk of death regardless of cause.

Studies conducted by Dr. Grøntved A,. Et al. such, is a meta-analysis of 8 clinical studies collected from the database 1974 to March 2011 without restrictions and by reviewing reference lists of retrieved articles.

Effect of Vitamin D for diabetes

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High levels of vitamin D in the blood appear to be associated with a reduced risk of incident diabetes in people at high risk for this disease, this is according to a recent report, presented Dr. Anastassios G. Pittas and colleagues from the division of endocrinology, diabetes, and metabolism, the Tufts New England Medical Center in Boston, Massachusetts which was presented at the American Diabetes Association 71st Scientific Sessions. According to Drs. Pittas, vitamin D may play a role in improving diabetes by increasing insulin secretion and insulin sensitivity, and most of the evidence focuses on the beneficial effects in pancreatic beta cells.
To determine the relationship between vitamin D status and risk of incident diabetes, the researchers analyzed data from the Diabetes Prevention Program (DPP), three groups of studies comparing intensive lifestyle

Monday, June 20, 2011

Drug Politerapi Antiepileptik During Pregnancy and Risk of Fetal Malformations

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During pregnancy, drug politerapi antiepileptik (OAE), which includes valproate sustained a risk of malformations in the fetus than politerapi without this drug. This finding is the result of the study dr. Lewis Holmes and colleagues, from MassGeneral Hospital for Children in Boston, which was published online in mid June 2011 in the Archives of Neurology. During this time, it is known that women who consume more than one type of OAE during pregnancy have a higher risk of having infants with severe congenital malformations, compared to pregnant women who use only one type of OAE. Studies conducted dr. Holmes and his team will further strengthen the evidence of close links politerapi OAE use by pregnant women with the risk of malformations in the fetus. The study, named the North American AED Registry revealed that the risk of malformations increased significantly in

Benefits and Risks Intra-arterial Chemotherapy for Retinoblastoma

Intra-arterial chemotherapy for the treatment of retinoblastoma can result in "dramatic response", but also raises the risk of side effects ranging from mild to severe. This finding revealed by dr. Carol Shields and colleagues, from the Wills Eye Institute Philadelphia, published in the Archives of Ophthalmology. In the study, intra-arterial chemotherapy (intra-arterial chemotherapy, IAC) was done in 17 children with retinoblastoma are aged 4 to 74 months. Complete response was found in 14 children and 10 of whom remained free of tumor when performed follow-up a year later.
Successful catheterization in 16 children with retinoblastoma median basal dimension of 20 mm and the average thickness of 9 mm. IAC is actually scheduled for 3 times with an interval of one month, but the researchers decided not to increase the cycles of chemotherapy if the tumor has shown complete regression. IAC is a primary therapy in 12 children, and the eyeball was saved in eight children among them - including all children who are classified as category C or D according to the International Classification of Retinoblastoma (scale categories: A through E; E most severe). Meanwhile, the eyeball is also saved on 2 of 4 children who underwent the IAC as a secondary therapy. Primary tumor regresses post-chemotherapy; basal dimensions shrink 31% and the thickness decreased 56%.
Tumor recurrence occurred in three children only once, each in the form of solid tumor, the seeds of the tumor in subretina (subretinal seeds), and the seeds of the tumor in the anterior chamber or glass body (anterior chamber or vitreous seeds). Enucleation had to be done in six children, external beam radiotherapy twice, and plaque radiotherapy once. Recognized researchers, IAC has a number of advantages over other therapeutic modalities for retinoblastoma cases, partly because the dose is small enough to do one day so enlarge the biological effects at the target location while minimizing toxic effects on other body parts. However, the IAC procedure is technically quite difficult, and children should be watched closely in order to be aware of the possibility of serious side effects. During follow-up period, reported some mild side effects of short duration, covering palpebra edema (in 13 children a month later), blefaroptosis (10 children), and orbital congestion (12 children), all of which recovered within 6 months. More serious side effects of oftalmika artery stenosis (3 cases of permanent, temporary 1 case) and central retinal artery occlusion (two cases of permanent, one temporary).
Researchers recommend that each health care center is working on fluorescein angiography IAC always do first in order to assess ocular blood flow, especially for detecting atrophy of the choroid. The team of researchers themselves have diagnosed five cases of choroid atrophy among patients who participated in this study. "The impact of atrophy of the choroid to the sharpness of vision can be very bad boy. In fact, enucleation should be performed on the eyeball atrophy choroid; if not, the child continues to be blind," said dr. Shields. Not encountered in cases of arterial embolism, metastasis, neurological defects, occlusion of the internal carotid artery or femoral artery, and stroke in children.
Thus, dr. Shields concludes that although retinoblastoma is very responsive to the IAC, the tendency should be wary of the emergence of toxic effects due to exposure to chemotherapy or radiotherapy. Therefore, the IAC for retinoblastoma should be considered with caution in certain cases.

Albumin levels is a predictor of nephropathy and cardiovascular events in patients with type 2 diabetes

Urinary albumin levels (UAC - Urinary albumin concentration) yan gdiperoleh of random checks can predict the presence of diabetic nephropathy, cardiovascular events, and death, as the ratio of albumin: creatinine (ACR) in patients with type 2 diabetes, according to the results of this study Dr. Luciana V. Viana, who delivered in the 93rd Annual Meeting of the Endocrine Society (Endo) in June 2011.
An examination of the urine is done randomly, using urine ACR, become the preferred method for diagnosing the presence of microalbuminuria, which is a risk factor for diabetic nephropathy, cardiovascular disease, and death. Although, several studies have assessed the benefits of using UAC in random urine tests for the

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