Urinary albumin levels (UAC - Urinary albumin concentration) yan gdiperoleh of random checks can predict the presence of diabetic nephropathy, cardiovascular events, and death, as the ratio of albumin: creatinine (ACR) in patients with type 2 diabetes, according to the results of this study Dr. Luciana V. Viana, who delivered in the 93rd Annual Meeting of the Endocrine Society (Endo) in June 2011.
An examination of the urine is done randomly, using urine ACR, become the preferred method for diagnosing the presence of microalbuminuria, which is a risk factor for diabetic nephropathy, cardiovascular disease, and death. Although, several studies have assessed the benefits of using UAC in random urine tests for the diagnosis of microalbuminuria.
Dr.Luciana V. Viana, of the Hospital de Clinicas de Porto Alegre and Federal University of Rio Grande do Sul, Porto Alegre, Brazil, and colleagues measured urinary albumin among 199 patients with type 2 diabetes. And patients were followed for 4.1 to 8.8 years.
A receiver operating characteristic curve (ROC) was made to determine the point of UAC is meaningful for the prediction of diabetic nephropathy. A UAC = 14 mg / L predicted diabetic nephropathy and predictions for this and other outcomes compared with traditional examinations microalbuminuria (ACR = 30 mg / g and urinary albumin excretion [UAE] = 30 mg/24 hours). The result is the frequency of diabetic nephropathy was 31.7% (23.5% reduction in glomerular filtration rate, 13.6% macroalbuminuria); new cardiovascular events by 26.4% and deaths by 8.50%. From the statistical analysis using the Cox-analysis revealed that the UAC of 14 mg / L to 4.30-fold increased risk for diabetic nephropathy outcome, 3.25 for cardiovascular events, and of 5.51 for death.
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